Affiliation:
1. State Key Laboratory of Medicinal Chemical Biology, College of Pharmacy and Tianjin Key Laboratory of Molecular Drug Research, Nankai University, 38 Tongyan Road, Haihe Education Park, Tianjin 300353, China
Abstract
Natural polysaccharide is a kind of natural macromolecular which can be extracted from
plants, fungi, algae, animals, and bacteria. The monosaccharide compositions and glucosidic bonds of
polysaccharides from different origins vary substantially. Natural polysaccharides have been shown to
possess complex, important and multifaceted biological activities including antitumor, anticoagulant,
antioxidative, antiviral, immunomodulatory, antihyperlipidemic and antihepatotoxic activities. Their
properties are mainly due to their structural characteristics. It is necessary to develop polysaccharide
immunomodulators with potential for preventive or therapeutic action. The present paper summarizes
the structural features, immunostimulatory activity and the immunomodulatory mechanisms of natural
polysaccharides. In particular, it also provides an overview of representative natural polysaccharide
immunomodulators.
Funder
Natural Science Foundation of Tianjin
Publisher
Bentham Science Publishers Ltd.
Subject
Drug Discovery,Pharmacology,General Medicine
Cited by
54 articles.
订阅此论文施引文献
订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献