Localized Zosteriform bullous Pemphigoid on the Sites of a Healed Herpes Zoster: A Case Report and Literature Review

Abstract

Background: Localized zosteriform bullous pemphigoid is a rare variant of bullous pemphigoid that is considered a manifestation of Wolf`s isotopic response. Only a few cases have been reported. We add another case to the body of knowledge in order to shed the light on this uncommon variant of bullous pemphigoid. Case Report: A 67-year old female patient developed vesiculobullous lesions at the sites of healed herpes zoster. The patient was diagnosed as a case of zosteriform bullous pemphigoid based on the clinical presentation and skin biopsy findings. Conclusion: Zosteriform bullous pemphigoid is a rare manifestation of Wolf`s isotopic response. A Skin biopsy must be performed early to ensure proper diagnosis and management.