Affiliation:
1. Department of Physics,
Narajole Raj College, Paschim Medinipur-721211, West Bengal, India
2. Department of Physics, Vidyasagar University, Paschim Medinipur-721102, West Bengal, India
Abstract
Abstract:
In recent years, the green synthesis of different metal nanoparticles has become a substantial
technique for the synthesis of different essential nanoparticles and their potential applications in
technological, industrial along with biomedical fields. Among the several essential nanoparticles, copper
nanoparticles (CuNPs) have attracted enormous attention for their wide range of applications like
the production of gas sensors, solar cells, high-temperature superconductors as well as drug delivery
materials and catalysis owing to its distinctive optical, electrical, dielectric, imaging and catalytic, etc.
properties. Herein, in this review, our aim is to find out the recent progress of synthesis, as well as different
optical and structural characterizations of green, synthesized CuNPs along with their broadspectrum
biomedical applications, mainly antibacterial, antifungal, antiviral and anticancer as well as
the future perspective of research trends in the green synthesis of CuNPs. CuNPs have been synthesized
by different researchers using three methods, namely, physical, chemical, and biological. In this
review, the eco-friendly, efficient and low cost different established biological/green synthesis methods
of CuNPs using different plant extracts like leaves, flowers, fruits, seeds, latex, etc., as capping
and reducing agents have been briefly discussed, along with reaction conditions together with their optical
as well as structural analysis. Effects of different parameters on the green synthesis of CuNPs like
the presence of phytochemicals and confirmation of phytochemicals, temperature, pH, etc., are elucidated.
Studies of the antibacterial activity of biomolecules capped CuNPs by different researchers
against both Gram-positive and Gram-negative bacterial strains along with minimum inhibitory concentration
(MIC) values have been summarized. Furthermore, antifungal and antiviral effects of green
synthesized CuNPs studied by different researchers are mentioned with minimum inhibitory concentration
(MIC) values. The anticancer activity of green synthesized CuNPs against different cancer cells
studied by different researchers is summarized with correlation sizes of CuNPs on anticancer activity.
The review also focuses on in vivo applications of green synthesized CuNPs along with clinical trails.
Furthermore, an emphasis is given to the effectiveness of CuNPs in combating COVID-19.
Publisher
Bentham Science Publishers Ltd.
Subject
Materials Science (miscellaneous),Biomaterials,Ceramics and Composites