A Mini-Review: Achievements in the Thiolysis of Epoxides

Author:

Chen Zhihua1,Nasr Saeed Mohammadi2,Kazemi Mosstafa3,Mohammadi Masoud3

Affiliation:

1. Institute of Computing Science and Technology, Guangzhou University, Guangzhou 510006, China

2. Independent Researcher, Jowlan 65136-8942, Hamedan, Iran

3. Department of Chemistry, Faculty of Science, Ilam University, PO Box, 69315516 Ilam, Iran

Abstract

The β-hydroxy sulfides are an important class of organosulfur compounds that have a key role in the synthesis of bioactive compounds containing biological and natural products. The thiolysis of epoxides is the most common and best route for the synthesis of β-hydroxy sulfides. During the last decade, the applications of a diverse range of catalysts and promoter agents in green and organic mediums as well as under solvent-free conditions for the regioselective ring-opening reactions of epoxides with thiols in order to synthesize β-hydroxy sulfides have been studied by various research groups. This review is focused on the important achievements reported in the literature for the thiolysis of epoxides.

Publisher

Bentham Science Publishers Ltd.

Subject

Organic Chemistry

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