Advances in Chemistry of 2-(Piperazin-1-yl) Quinoline (Part IV)

Author:

El-Bana Ghada G.12,Gouda Moustafa A.13

Affiliation:

1. Department of Chemistry, Faculty of Science, Mansoura University, El-Gomhoria Street, Mansoura, 35516, Egypt

2. Mansoura University Student's Hospital, Mansoura University, El-Gomhoria Street, Mansoura ET, 35516, Egypt

3. Department of Chemistry, Faculty of Science and Arts, Taibah University, Ulla, Medina, Saudi Arabia

Abstract

Abstract: This review described the preparation of 2-(piperazin-1-yl) quinoline derivatives from 2- haloquinolines and anilides, which underwent alkylation, arylation, acylation, and reductive amination to form the 2-piprazinoquinolines. 2-(Piperazin-1-yl) quinoline used as building blocks for the synthesis of polyfunctionalized heterocyclic compounds with pharmacological interest.

Publisher

Bentham Science Publishers Ltd.

Subject

Organic Chemistry

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