Recent Advances of Water-Soluble Fullerene Derivatives in Biomedical Applications

Author:

Zhang Xiaoyan1,Cong Hailin1,Yu Bing1,Chen Qun1

Affiliation:

1. Institute of Biomedical Materials and Engineering, College of Materials Science and Engineering, Qingdao University, Qingdao 266071, China

Abstract

Fullerenes, especially C60, exhibit great potential applications in biology field, due to their excellent antibacterial, antiviral, antitumor and other properties. Many water-soluble fullerene derivatives have been designed, synthesized and used as photo-dynamic therapy agents, antiviral agents, bioimaging agents, drug carriers and so on. This review focuses on the usage of water-soluble fullerene derivatives in biomedical field in recent years. The first half gives the preparation of water-soluble fullerene derivatives themselves with covalent bonds and non-covalent bonds. In the second half, myriad applications of water-soluble fullerene derivatives in biomedical field are introduced.

Funder

Postdoctoral Scientific Research Foundation of Qingda

China Postdoctoral Science Foundation

Innovation Leader Project of Qingdao

People's Livelihood Science and Technology Project of Qingdao

Project of Shandong Province Higher Educational Science and Technology Program

Key Research and Development Project of Shandong Province

Major Science and Technology Innovation Project of Shandong Province

Taishan Young Scholar Program of Shandong Province

National Natural Science Foundation of China

Publisher

Bentham Science Publishers Ltd.

Subject

Organic Chemistry

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