One-Pot Multicomponent Synthesis of Imidazole Rings in Acidic Ionic Liquids: A Review-Reference-Cited by-同舟云学术

One-Pot Multicomponent Synthesis of Imidazole Rings in Acidic Ionic Liquids: A Review

Published:2020-12-24 Issue:8 Volume:17 Page:975-990
ISSN:1570-193X
Container-title:Mini-Reviews in Organic Chemistry
language:en
Short-container-title:MROC

Author:

Eze Cosmas Chinweike¹^ORCID,Ezeokonkwo Mercy Amarachi²^ORCID,Ezema Benjamin Ebere²^ORCID,Onoabedje Abraham Efeturi²^ORCID,Ibeanu Fidelia Ngozika¹^ORCID,Ugwu David Izuchukwu²^ORCID,Onyeyilim Leonard Ebuka²^ORCID,Ezugwu James Anayochwkwu²^ORCID

Affiliation:

1. Natural Science Unit, School of General Studies, University of Nigeria, Nsukka, Enugu State 410001, Nigeria

2. Department of Pure & Industrial Chemistry, University of Nigeria, Nsukka, Enugu State 410001, Nigeria

Abstract

The design of the environmentally friendly approach to the synthesis of biologically important compounds without compromising the yield has been the focus of many chemists in recent years. The development of the one-pot synthesis of heterocycles in the presence of Ionic Liquids (ILs), used as both environmental media and catalysts, is efficient and environmentally sustainable. This review highlights the one-pot synthesis of imidazoles in acidic ILs in the past decade. Some reviews have been conducted on imidazoles, such as their pharmacological importance. Hence, we decided to focus on their synthesis in acidic ionic liquids, which the authors are not aware of any published literature.

Publisher

Bentham Science Publishers Ltd.

Subject

Organic Chemistry

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