Affiliation:
1. Peking University Institute of Cardiovascular Sciences, Peking University Health Science Center, Key Laboratory of Molecular Cardiovascular Sciences, Ministry of Education, 38 Xueyuan Road, Beijing 100191, China
Abstract
:
As a medicinal fungus, Inonotus obliquus (IO) has been widely used in the treatment of
cancer and digestive system diseases. Despite the progress that has been made in the studies of IO
and its active compounds, their applications in the treatment of other important clinical diseases, such
as cardiovascular diseases, which are major global issues with limited treatment strategies, are seldom
reported. This review summarizes the separation and purification methods of chemical components
of IO, the advances in their applications, and research progress on the pharmacological effects
and related mechanisms of IO in disease prevention. This review will help researchers and clinicians
to further understand the pharmacological functions and mechanisms of IO and its active components,
which may extend their medical applications in the prevention and treatment of other diseases
in addition to tumors and digestive system diseases in the near future.
Funder
National Natural Science Foundation of China
Publisher
Bentham Science Publishers Ltd.
Cited by
7 articles.
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