Affiliation:
1. Department of Pharmaceutical Chemistry and Quality Assurance, St. John Institute of Pharmacy and Research,
Palghar, Maharashtra, India
Abstract
:
To overcome the upsurge of antimicrobial resistance that has emerged in recent years,
there is a need for the development of newer hits having satisfying anti-infective activity. Hydrazides
incorporated with an azomethine hydrogen account for a cardinal class of molecules for the
development of newer derivatives. Hydrazide derivatives have gained considerable interest of medicinal
chemists owing to their diverse bioactivity. In the present review, we have attempted to
compile the recent trends in the synthesis of hydrazides and their substituted derivatives. The structural
features that lead to the desired antimicrobial activity are highlighted, which will lead the way
for synthetic and medicinal chemists to focus on newer designs in this arena.
Publisher
Bentham Science Publishers Ltd.
Cited by
2 articles.
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