Affiliation:
1. Laboratory of Applied Organic Chemistry, Faculty of Science and Techniques, Sidi Mohamed Ben Abdellah University,
B.P. 2202, Route d ‘Imouzzer, Fez, 30050, Morocco
Abstract
Abstract:
The chemistry of 2-quinolones derivatives has received more attention in organic chemistry
and medicinal chemistry. Moreover, several advancements in the application of this family of
compounds are considered to be of great utility. In recent years, a variety of new, effective, and
novel synthetic approaches (including green chemistry, catalyzed and microwave-assisted synthesis)
have been discovered and developed for the designing of safe and non-toxic 2-quinolone-based
scaffolds to investigate their antibacterial activities. This review summarizes the results of the literature
on the synthesis strategies of 2-quinolones derivatives and their reactivity, as well as their antibacterial
evaluations against different bacteria strains.
Publisher
Bentham Science Publishers Ltd.