Affiliation:
1. Department of Chemistry, Indian Institute of Technology Kanpur, 208016, Kanpur, Uttar Pradesh, India
Abstract
Multiheteroatom-containing small-sized cyclic molecules such as 2-
iminothiazolidines are often found to possess beneficial pharmacological properties. In this
review article, the biological significance of 2-iminothiazolidines is discussed and the literature
reports published in the last 15 years spanning from 2006 to 2020 describing various
preparative routes to access 2-iminothiazolidine derivatives have been categorically and
chronologically described. The notable synthetic methods discussed here involve ringexpansion
transformations of nonactivated and activated aziridines, thiiranes, epoxides, and
other miscellaneous reactions.
Publisher
Bentham Science Publishers Ltd.
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