The Molecular Diversity Scope of Oxindole Derivatives in Organic Synthesis

Abstract

The role of oxindole derivatives is discussed as starting materials in diverse organic reactions, including two and more components, between the years 2014 until 2020. Oxindoles are famous because of their biological properties. For instance, chromanone-fused polycyclic pyrrolidinyl-dispirooxindoles, functionalized polycyclic spiro-fused carbocyclicoxindole, and 3,3-disubstituted oxindoles have anti-cancer, anti-tumor, and anti-microbial properties, respectively. Therefore, various methods for synthesizing the oxindole structures have received much attention in organic chemistry.