Dendrimer applications: a brief review

Abstract

: Dendrimers are highly branched three-dimensional macromolecules with a highly controlled structure, a single molecular weight, numerous controllable dendritic branches and peripheral functionalities, as well as the tendency to adopt an ellipsoid or spheroid shape once a certain size is reached. These features have made them attractive for application in pharmaceutical and medicinal chemistry in gene transfection, as medical imaging agents, and as drug carriers in potential drug delivery agents. The incorporation of metallic species into dendritic molecules has also been reported; the focus has been on organometallic dendrimers with metallic species only at specific positions of the molecules, such as the core, dendritic branches and the periphery, studied for their magnetic, electronic, and photo-optical or catalytic properties. Dendrimers have been investigated for optoelectronic applications (adsorption, emission, laser emission, nonlinear optics) through the encapsulation of active units by dendritic branches, core and peripheral. This review briefly discusses their use in nanomedicine, cancer treatment, treatment of other diseases, tissue repair, catalysis and applications in OLEDs and solar cells.