Epstein-Barr Encephalitis in a Child with Congenital Human Immunodeficiency Virus Infection: A Case Report Calling for No Forgetfulness

Author:

Tsiatsiou Olga1,Papachristou Savvas2,Papadimitriou Eleni1,Michailidou Elisavet1,Chatzidimitriou Dimitrios3,Papa Anna3,Doulioglou Vai4,Karyda Stavroula4,Antachopoulos Charalampos2,Roilides Emmanuel2

Affiliation:

1. Pediatric Infectious Diseases Unit, 1st and 3rd Departments of Pediatrics, Faculty of Medicine, Aristotle University School of Health Sciences, Hippokration General Hospital of Thessaloniki, Thessaloniki, Greece

2. 3rd Department of Pediatrics, Faculty of Medicine, Aristotle University School of Health Sciences, Hippokration General Hospital of Thessaloniki, Thessaloniki, Greece

3. Department of Microbiology, Faculty of Health Sciences, School of Medicine, Aristotle University of Thessaloniki, Thessaloniki, Greece

4. Department of Pediatrics, G. Genimatas General Hospital, Thessaloniki, Thessaloniki, Greece

Abstract

Background: In resource-rich settings, the rate of mother-to-child transmission of human immunodeficiency virus (HIV) has dramatically decreased by virtue of a combination of preventive strategies during the last two decades. Case Presentation: We present a case of progressive developmental milestone loss in a toddler with previously unknown congenitally acquired human immunodeficiency virus (HIV) infection, complicated by an Epstein-Barr virus (EBV) coinfection. Conclusion: Our report underscores the differential diagnosis between HIV encephalopathy and EBV encephalitis and the vertical transmission of the HIV infection, which constitutes an alarming issue in terms of public health.

Publisher

Bentham Science Publishers Ltd.

Subject

Virology,Infectious Diseases

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