Advantages of Self-assembled Nano Peptide Hydrogels in Biological Tissue Engineering

Author:

Sun Nianfeng1,Tian Ailing2,Xue Junshuai2

Affiliation:

1. Women\'s and Children\'s Hospital Affiliated to Qingdao University, Qingdao, 266001, China

2. Qilu Hospital of Shandong University, Ji’nan 250012, China

Abstract

Abstract: With the development of tissue engineering research, biological scaffolds have been widely studied and applied in the field of regenerative medicine. Self-assembling nanopeptide hydrogels have good biocompatibility, and their seed cells can be used for their biological activities and have no toxic side effects. The products can be absorbed and degraded by the organism and have great advantages in tissue engineering and regenerative medicine. Studies have shown that the self-assembled nano peptide hydrogel and adipose-derived mesenchymal stem cells (ADMSCs) mixed solution are "biological ink". 3D related biological printing technology can be used to print related tissue models and induce ADMSCs to differentiate into blood vessels. It is further illustrated that the use of self-assembled nano peptide hydrogel scaffolds to load stem cells has a good application prospect in stem cell transplantation and 3D biological printing.

Funder

Natural Science Foundation of Shandong Province

Natural Science Foundation Program of Shandong Province

Publisher

Bentham Science Publishers Ltd.

Subject

Cell Biology,Molecular Biology,Biochemistry,General Medicine

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