Biomedical Applications of Lectins from Traditional Chinese Medicine

Author:

Singh Senjam Sunil1,Wong Jack Ho2,Ng Tzi Bun2,Singh Wayenbam Sobhachandra1,Thangjam Robert3

Affiliation:

1. Laboratory of Protein Biochemistry, Biochemistry Department, Manipur University, Canchipur, Imphal-795003, India

2. School of Biomedical Sciences, Faculty of Medicine, The Chinese University of Hong Kong, Shatin, Hong Kong, China

3. Department of Biotechnology, School of Life Sciences, Mizoram University, Aizawl - 796 004, India

Abstract

Lectins are proteins or glycoproteins of non-immune origin which have at least one noncatalytic domain that bind reversibly to specific mono or oligosaccharides. Traditional Chinese Medicine (TCM) involves a broad range of medicinal practices sharing common concepts which have been developed in China and are based on a tradition of more than thousands of years. Plant materials which are commonly used in TCM as a complementary or alternative for Western medical treatments contain a considerable number of important lectins. These lectins have been reported to have various applications and uses such as cancer treatment, glycoconjugate research, biomarker development, and others. Here, we summarize the available literature related to lectins from TCM and recent trends in their potential biomedical applications.

Funder

National Natural Science Foundation of China

Food and Health Bureau, The Government of Hong Kong Special Administrative Region,

Publisher

Bentham Science Publishers Ltd.

Subject

Cell Biology,Molecular Biology,Biochemistry,General Medicine

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