Research and Development of Proteins and Peptides with Therapeutic Potential from Yam Tubers
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Published:2019-01-01
Issue:3
Volume:20
Page:277-284
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ISSN:1389-2037
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Container-title:Current Protein & Peptide Science
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language:en
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Short-container-title:CPPS
Author:
Zhang Liang1, Ng Tzi Bun2, Lam Jenny Ka Wing3, Wang Shi Wei1, Lao Lixing1, Zhang Kalin Yanbo1, Sze Stephen Cho Wing4
Affiliation:
1. School of Chinese Medicine, Li Ka Shing Faculty of Medicine, the University of Hong Kong, Hong Kong SAR, China 2. School of Biomedical Sciences, Faculty of Medicine, the Chinese University of Hong Kong, Hong Kong SAR, China 3. Department of Pharmacology and Pharmacy, Li Ka Shing Faculty of Medicine, the University of Hong Kong, Hong Kong SAR, China 4. Department of Biology, Faculty of Science, Hong Kong Baptisit University, Hong Kong SAR, China
Abstract
We discuss the diverse biological activities, therapeutic potential, and clinical applications of
peptides and proteins isolated from various yams species including Dioscorea opposita Thunb (Chinese
yam), D alata, D japonica (Japanese yam), D pseudojaponica, D batatas (Korea yam), and D cayenensis.
Yam peptides and proteins have many pharmacological activities including immunomodulatory, antioxidant,
estrogen-stimulating, osteogenic, angiotensin I-converting enzyme inhibiting, carbonic anhydrase
and trypsin inhibiting, chitinase, anti-insect, anti-dust mite, lectin, and anti-proliferative activities.
Yam peptides and proteins have therapeutic potential for treating cardiovascular diseases, inflammatory
diseases, cancers, aging disorders, menopause, and osteoporosis.
Funder
Seed Funding Programme for Basic Research, the University of Hong Kong Innovation and Technology Commission - Government of Hong Kong Special Administrative Region
Publisher
Bentham Science Publishers Ltd.
Subject
Cell Biology,Molecular Biology,Biochemistry,General Medicine
Reference38 articles.
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