Comparative Assessment of Antibacterial Efficacy of Commercially Available Different Dental Gels: An In-vitro Study

Abstract

Background: The topical routes of administering drug have certain visible advantages as direct application of a drug to the site of action and persistence of action for prolonged duration. More stability and better application property of gel cause its use for topical application. Objectives: To determine and compare antibacterial efficacy of commercially available different dental gels. Methods: For the evaluation of antibacterial efficacy of commercially available different antiseptic gels on Streptococcus mutans and Lactobacillus acidophilus well-diffusion method was used. To assess the antibacterial efficacy after incubation in appropriate culture medium diameter of zone of inhibition was measured. Results: Maximum zone of inhibition was found with Cure next gel (40 mm,40mm) followed by Hexigel (30 mm, 21mm), Mucopain (17 mm, 17mm), and Dologel (7 mm, 16mm) against S. mutans and L. acidophilus, respectively. Analysis of variance (ANOVA) and Post Hoc Test were used to analyze results statistically. The difference between commercially available different dental gels was statistically significant (P < 0.001) at a 5%. Conclusion: In the present study, it was seen that Curenext gel was more effective followed by Hexigel, Mucopain gel and Dologel on S. Mutans and L. Acidophilus.