Affiliation:
1. Department of Biological Sciences, Faculty of Science, King Abdulaziz University, Jeddah, Saudi Arabia
Abstract
Background:
Several computational tools assist in predicting the chemical properties,
toxicity, solubility, and binding affinity of the drugs.
Objective:
The study aims to experimentally analyze the efficiency of the antimalarial drug “sulfadiazine”
in a higher dose in contrast to its conventional use.
Methods:
The antimalarial drug was screened, and its application was assessed on the host (mice).
Results:
The results showed that parasitemia of the infected control group was significantly higher
than the others (P<0.0001) on days 3, 5, 7, and 9. The parasitemia of the IT+4 group was significantly
lower than the parasitemia of the IT-4 group on the 15th day.
Conclusion:
It was concluded that increased potency for the antimalarials is because they are nontoxic.
Publisher
Bentham Science Publishers Ltd.
Subject
Infectious Diseases,Pharmacology
Cited by
2 articles.
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