Author:
Inwoley André,Affi-Aboli Roseline,Kabran Matthieu,Adiko Aimé Césaire,Abiyou Nadège-Audrey,Amani Franck Stéphane,Seka Jean-Claude,Dembele Bamory
Abstract
Introduction:In Africa, the Widal test is done in the majority of laboratories by rapid tests whose performances are poorly documented. We evaluate the performance of 9 commercial rapid tests used in Côte d'Ivoire for the serodiagnosis of typhoid and paratyphoid fever.Methods:we used a panel of 170 samples collected from subjects suspected of typhoid or paratyphoid fever in Abidjan to determine the sensitivity, the specificity and operational characteristics of 9 plate agglutination tests (BIOREX®, BIOTEC®, CHRONOLAB®, CROMATEST®, FORTRESS®, PLASMATEC®, CYPRESS®, SPINREACT®and TYDAL®) compared to the reference technique SALMONELLA SEROLOGY®of BIORAD (tube agglutination).Results:Among the 9 evaluated tests, only BIOTEC®presented good performances (96% sensitivity and 97% specificity). Others gave sensitivities below 80%. Their characteristics were improved with the semi-quantitative plate agglutination test. All tests had good operational characteristics.Conclusion:In our context, the majority of tests evaluated should not be used to carry out the Widal test.
Publisher
Bentham Science Publishers Ltd.
Subject
General Materials Science
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