Affiliation:
1. Institute of Pharmaceutical Research, GLA University, Mathura, India
Abstract
Background:
Brain disorders are presently one of the most serious and challenging
health issues in the world. A significant portion of morbidities and fatalities worldwide are caused
by these brain disorders. Parkinson's disease (PD) is a neurological condition that develops when
dopaminergic neurons are lost in the substantia nigra, causing cognitive and motor impairment.
Objectives:
Conventional treatment modalities, including dopamine replacement therapy and
optimization of dopaminergic transmission approaches, don’t address the pathogenic processes
primary to the symptoms of PD and usually become the least essential with time. Researchers are
aiming to provide effective treatment in treating PD with minimizing adverse consequences. In
the past few years, a number of studies on nutraceuticals have been conducted to produce foods
with fewer adverse effects and increased therapeutic effectiveness. The use of these nutraceuticals
is typically risk-free and can be coupled with the patient's current common pharmacological therapy
to enhance the standard of living and lessen PD symptoms.
Conclusion:
The current review focuses on a number of important nutritional compounds and dietary
changes that have been shown to be effective against a number of the pathogenic pathways
involved in the onset and progression of Parkinson's disease (PD), and further lights the justification
for their prospect use in the treatment and prevention of PD.
Publisher
Bentham Science Publishers Ltd.
Subject
Public Health, Environmental and Occupational Health,Nutrition and Dietetics,Food Science
Cited by
4 articles.
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