Affiliation:
1. Nanotechnology Department, School of Advanced Technologies, Iran University of Science and Technology, Tehran,Iran
2. Interdisciplinary Technologies Department, Breast Cancer Research Center, Motamed Cancer Institute, ACECR, Tehran,Iran
Abstract
As calcium phosphate micro/nano-structures (CPMNS) have been suggested, many protocols
have been exploited to design new formulations. CPMNS are similar to a bone mineral from the
point of view of structure and chemical composition. Some of them, such as hydroxyapatite (HAp),
have been commercialized, and they demonstrated sufficient efficiency as hard tissue replacements
for various purposes. Due to their biocompatibility, bioaccumulation, bioactivity, osteogenic activity,
and anticancer properties, as well as great resemblance to body organs such as bones, these substances
are suitable options for the diagnosis and treatment of various diseases. Therefore, recent advances
of HAp applications in drug delivery for various diseases, such as cancer, bone disease, and tooth inflammation,
are reviewed. Moreover, their implementation for several kinds of drugs, including anticancer,
anti-inflammatory, antibiotics, growth factors and analgesics, is investigated.
Publisher
Bentham Science Publishers Ltd.
Subject
General Earth and Planetary Sciences,General Environmental Science
Cited by
6 articles.
订阅此论文施引文献
订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献