Assessment of Memory Impairment in Early Diagnosis of Alzheimer’s Disease

Author:

Vyhnálek Martin1,Marková Hana1,Laczó Jan1,De Beni Rossana2,Di Nuovo Santo3

Affiliation:

1. Memory Clinic, Department of Neurology, Charles University, 2nd Faculty of Medicine and Motol University Hospital, Prague, Czech Republic

2. Department of Psychology, University of Padua, Padua, Italy

3. Department of Education, University of Catania, Catania, Italy

Abstract

Memory impairment has been considered as one of the earliest clinical hallmarks of Alzheimer’s disease. This paper summarizes recent progress in the assessment of memory impairment in predementia stages. New promising approaches of memory assessment include evaluation of longitudinal cognitive changes, assessment of long-term memory loss, evaluation of subjective cognitive concerns and testing of other memory modalities, such as spatial memory. In addition, we describe new challenging memory tests based on memory binding paradigms that have been recently developed and are currently being validated.

Funder

European Regional Development Fund

Ministry of Health of the Czech Republic

MH CZ - DRO

National Program of Sustainability II

Charles University

Publisher

Bentham Science Publishers Ltd.

Subject

Clinical Neurology,Neurology

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