Perturbations in Microbiota Composition as a Novel Mediator in Neuropsychiatric, Neurological and Mental Disorders: Preventive and Therapeutic Complementary Therapies to Balance the Change

Author:

Moghadam Majid Taati12,Ramírez-Coronel Andrés Alexis345,Darijani Samaneh6,Akbarizadeh Majid Reza7,Naderifar Mahin8,Soltaninejad Simin9,Shahbazi Shahla10,Dousari Amin Sadeghi11,Mojtahedi Ali2,Akhavan-Sigari Reza1213

Affiliation:

1. Student Research Committee, Iran University of Medical Sciences, Tehran, Iran

2. Department of Microbiology, School of Medicine, Iran University of Medical Sciences, Tehran, Iran

3. Laboratory of Psychometrics, Comparative Psychology and Ethology (LABPPCE), Azogues Campus Nursing Career, Health and Behavior Research Group (HBR), Catholic University of Cuenca, Ecuador

4. Epidemiology and Biostatistics Research Group, CES University, Medellín, Colombia

5. Department of Psychology, University of Palermo, Buenos Aires, Argentina

6. School of Medicine, Bam University of Medical Sciences, Bam, Iran

7. School of Medicine, Zabol University of Medical Sciences, Zabol, Iran

8. School of Nursing & Midwifery, Zabol University of Medical Sciences, Zabol, Iran

9. Department of Radiation Oncology, Afzalipour Hospital, Kerman University of Medical Sciences, Kerman, Iran

10. Department of Molecular Biology, Pasteur Institute of Iran, Tehran, Iran

11. Jiroft University of Medical Sciences, Jiroft, Iran

12. Department of Neurosurgery, University Medical Center Tuebingen, Tuebingen, Germany

13. Department of Health Care Management and Clinical Research, Collegium Humanum Warsaw Management University, Warsaw, Poland

Abstract

Abstract: Although microbiology and neurology are separate disciplines, they are linked to some infectious and neurological diseases. Today, microbiome is considered as one of the biomarkers of health by many researchers. This has led to the association of microbiome changes with many neurological diseases. The natural microbiota has many beneficial properties. If disrupted and altered, it can lead to irreversible complications and many neurological diseases. Therefore, according to previous studies, some preventive and therapeutic complementary therapies can prevent or restore microbiome dysbiosis and inflammation in the nervous system. With our current perception of the microbiological basis for different neurological disorders, both aspects of drug treatment and control of perturbations of the microbiome should be considered, and targeting them simultaneously will likely help to attain favorable results.

Publisher

Bentham Science Publishers Ltd.

Subject

Neurology (clinical),Neurology

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