Natural Bioactive Compounds against Oxidative Stress: Dietary Polyphenols Strike Back

Author:

Cantore Stefania1,Arrigoni Roberto2,Cammarota Francesco3,Porro Rosa4,Dioguardi Mario5,Cazzolla Angela Pia5,De Leonardis Francesco3,Polimeno Lorenzo6,Zerman Nicoletta7,Di Cosola Michele5,Mastrangelo Filiberto5,Santacroce Luigi8,Ballini Andrea9

Affiliation:

1. Independent Researcher, Sorriso & Benessere- Ricerca e Clinica, Bari, Italy

2. CNR Institute of Biomembranes, Bioenergetics and Molecular Biotechnologies (IBIOM), Bari, Italy

3. Department of Bioscience, Biotechnology and Biopharmaceutics, University of Bari, Bari, Italy

4. Department of Informatics, University of Bari “Aldo Moro”, Bari, Italy

5. Department of Clinical and Experimental Medicine, University of Foggia, Foggia, Italy

6. Polypheno Academic Spin off, School of Medicine, University of Bari "Aldo Moro", Bari, Italy

7. Department of Surgical, Dentistry, Maternal and Child Sciences, University of Verona, Verona, Italy

8. Department of Interdisciplinary Medicine, Microbiology and Virology Unit, University of Bari "Aldo Moro", Bari, Italy

9. University of “Aldo Moro”, Bari, Department of Precision Medicine, University of Campania “Luigi Vanvitelli”, Naples, Italy

Abstract

Abstract: Oxidative stress is a major cellular and metabolic burden that can really alter cell life and become the base for disease onset and development. Many widespread pathologies can develop from an unresolved oxidative stress situation; thus, addressing this state is paramount for human health. Our antioxidant enzymes sometimes are not just enough. Fortifying our defense and the antioxidant and anti-inflammatory system can make a difference in our health: if this is attainable with our dietary habits, it could be a dream come true. Polyphenols are a fantastic tool indeed in the fight against oxidative stress: they are easy to obtain, with little cost, no side effects, and have a multitude of metabolic actions. This perspective review would shed light on polyphenol’s metabolic and molecular action regarding oxidative stress to help preserve our health.

Publisher

Bentham Science Publishers Ltd.

Subject

Immunology and Allergy,Endocrinology, Diabetes and Metabolism

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