Affiliation:
1. Department of Pharmaceutical Sciences, M.M. College of Pharmacy, Maharishi Markandeshwar (Deemed to be University),
Mullana, Ambala, Haryana-133207, India
Abstract
Background:
Various nutraceuticals from different sources have various beneficial
actions and have been reported for many years. The important findings from the research
conducted using various nutraceuticals exhibiting significant physiological and pharmacological
activities have been summarized.
Methods:
An extensive investigation of literature was done using several worldwide electronic
scientific databases like PUBMED, SCOPUS, Science Direct, Google Scholar, etc. The
entire manuscript is available in the English language that is used for our various compounds
of interest. These databases were thoroughly reviewed and summarized.
Results:
Nutraceuticals obtained from various sources play a vital role in the management of
peripheral neuropathy associated with diabetes. Treatment with nutraceuticals has been beneficial
as an alternative in preventing the progression. In particular, in vitro and in vivo studies
have revealed that a variety of nutraceuticals have significant antioxidant and anti-inflammatory
properties that may inhibit the early diabetes-driven molecular mechanisms that induce
DPN.
Conclusion:
Nutraceuticals obtained from different sources like a plant, an animal, and marine
have been properly utilized for the safety of health. In our opinion, this review could be
of great interest to clinicians, as it offers a complementary perspective on the management of
DPN. Trials with a well-defined patient and symptom selection have shown robust pharmacological
design as pivotal points to let these promising compounds become better accepted
by the medical community.
Publisher
Bentham Science Publishers Ltd.
Subject
Immunology and Allergy,Endocrinology, Diabetes and Metabolism