Autoimmune Polyendocrine Syndrome Complicated by Pulmonary Hypertension-Reference-Cited by-同舟云学术

Autoimmune Polyendocrine Syndrome Complicated by Pulmonary Hypertension

Published:2021-03 Issue:3 Volume:21 Page:561-565
ISSN:1871-5303
Container-title:Endocrine, Metabolic & Immune Disorders - Drug Targets
language:en
Short-container-title:EMIDDT

Author:

Disoteo Olga E.¹^ORCID,Zampetti Benedetta²^ORCID,Garascia Andrea³^ORCID,Attanasio Roberto⁴^ORCID,Cozzi Renato²^ORCID

Affiliation:

1. ASST Grande Ospedale Metropolitano Niguarda, Diabetology Unit, Milan,Italy

2. ASST Grande Ospedale Metropolitano Niguarda, Endocrinology Department, Milan,Italy

3. ASST Grande Ospedale Metropolitano Niguarda, Cardiology Unit, Milan,Italy

4. IRCCS Orthopedic Institute Galeazzi, Endocrinology Service, Milan,Italy

Abstract

A 24-years old female was admitted for acute renal failure, melanoderma, hyponatremia, and hyperkalemia. The clinical suspicion of Addison’s disease was confirmed by laboratory test and the appropriate replacement therapy with corticosteroids and fludrocortisone was started. In the meantime primary hypothyroidism and diabetes mellitus type 1 were disclosed and treated, thus fulfilling a diagnosis of autoimmune polyendocrine syndrome type 2. Eighteen months later she was admitted for right-sided heart failure. The work-up allowed to diagnose pulmonary arterial hypertension. Here, we report the clinical course and discuss the putative link between these two rare diseases.

Publisher

Bentham Science Publishers Ltd.

Subject

Immunology and Allergy,Endocrinology, Diabetes and Metabolism

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