Affiliation:
1. Department of Ophthalmology, Inonu University Turgut Ozal Medical Center, Malatya, Turkey
2. Department of Biochemistry, Inonu University Turgut Ozal Medical Center, Malatya, Turkey
Abstract
Objective: To investigate whether serum vitamin D levels have an effect on
pseudoexfoliation (PEX) glaucoma/syndrome development and on the control of glaucoma in these
cases.
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Method: A total of 31 cases with PEX glaucoma, 34 cases with the PEX syndrome and 43 control
subjects of similar age and sex were included in the study. Vitamin D levels were compared between
the groups and also between the cases where glaucoma surgery was performed or not.
Results:
PEX glaucoma group consisted of 17 males and 14 females, PEX syndrome group of 27
males and 7 females, and the control group of 27 males and 16 females. The mean age was 70.9±8.9
years, 72.1±7.3 years, and 67.9±9.1 years in PEX glaucoma, syndrome and control group, respectively.
Mean vitamin D levels were 9.4±7.7 ng/mL, 7.9±6,1 ng/mL, 11.5±14.2 ng/mL in PEX glaucoma, syndrome
and control group, respectively (p>0.05). The mean serum vitamin D level was 8.04±4.7 ng/mL
in those who underwent glaucoma surgery and 10.1±8.7 ng/mL in those who didn't undergo glaucoma
surgery in PEX glaucoma group (p>0.05). No difference was found between the PEX glaucoma subgroups
in terms of the mean deviation when classified according to vitamin D levels (<10 ng/mL, ≥10
ng/mL) (p>0.05).
Conclusion:
Although we found no statistically significant difference between the PEX syndrome/
glaucoma, and control group in terms of serum vitamin D levels, serum vitamin D levels were
lower in PEX syndrome and glaucoma group than control group. Our results indicate that serum vitamin
D levels have no effect on the development of PEX glaucoma/syndrome or the control of the disorder
in cases with PEX glaucoma. However, these results need to be supported with further studies on
a larger number of patients and with longer follow-up.
Funder
Inonu University Scientific Research Projects Coordination Unit
Publisher
Bentham Science Publishers Ltd.
Subject
Immunology and Allergy,Endocrinology, Diabetes and Metabolism
Cited by
5 articles.
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