Comparative treatment scheme between nitrofurantoin and ampicillin in pregnant patients 12 to 16 weeks, gestation with asymptomatic bacteriuria

Abstract

Urinary tract infection is a frequent cause of demand for care in family medicine, it can have a significant participation in maternal and neonatal morbidity. Objective. To compare the treatment scheme 7 with the antibiotic ampicillin in cases of asymptomatic bacteriuria in pregnant women with 12 to 16 weeks of gestation against nitrofurantoin. Material and methods. Observational, cross-sectional, retrospective and analytical study conducted in pregnant patients between weeks 12 and 16 of gestation with asymptomatic bacteriuria. Result. In patients with asymptomatic bacteriuria, a greater persistence of the infection was found when being treated with nitrofurantoin. Pregnant patients with 13 weeks had the highest incidence of asymptomatic bacteriuria with a frequency of 31.82 %. Conclusions. Nitrofurantoin may be considered a better treatment option than ampicillin, given its lower incidence rate of asymptomatic bacteriuria in pregnant patients at 12 to 16 weeks' gestation.