Scientific substantiation of the use of iron-containing drugs in veterinary medicine

Abstract

The relevance of this study is conditioned by the need to summarise current knowledge about the use of iron-containing drugs in veterinary medicine and their scientific substantiation. The purpose of this study was to analyse the results of the latest experimental data presented in the literature on the pharmacological and toxicological properties of iron-containing drugs and the specific features of their use in veterinary medicine. The study employed the method of literature analysis with the formulation of relevant substantiated conclusions and their generalisation or comparison. Iron-containing medicines are particularly relevant in modern veterinary medicine for the prevention of iron deficiency anaemia in piglets. The use of iron dextran preparations is a scientifically sound and necessary preventive measure in modern pig production. Furthermore, the study covered new approaches to the development of effective antianaemic drugs for animals of other species, including calves. The study also covered the controversial issues of the use of iron-containing drugs in pregnant females for the prevention of iron deficiency in animals born from them. The analysis of the literature data presented in this study shows a prominent degree of scientific interest in the study of pharmacological and toxicological properties of iron in high valences (specifically, ferrous iron in clathrochelate form) with a view to their use in medicine. The conducted literature review suggests the multidirectional use of iron-containing drugs in various dosage forms in veterinary medicine. The study identified the key trends in the pharmaceutical market of iron-containing drugs registered in Ukraine. In recent years, there has been a growing body of scientifically based evidence indicating the effectiveness of iron-dextran complex in combination with micro- and macronutrients and vitamins. Currently, the use of iron-containing drugs in the world’s veterinary practice, considering their scientifically and experimentally proven pharmacological properties, is extremely promising. The materials of this study are of practical value for expanding the possibilities of using new forms of iron in veterinary medicine