A survey assessing the role of a fixed-dose combination of 0.3% adapalene with 2.5% benzoyl peroxide in acne vulgaris

Abstract

Acne is a common skin condition affecting adolescents and young adults, characterized by the blockage of sebaceous glands along with bacterial colonization of the follicular duct and inflammation. Collagen and tissue damage secondary to acne inflammation brings about severe skin texture changes, including scarring. Timely treatment initiation is crucial to prevent acne progression to scarring. Topical retinoids, topical oral antimicrobials, or a combination of both are recommended as the first-line therapy for acne. The objective of the present survey was to assess the role of 0.3% adapalene/2.5% benzoyl peroxide (BPO) combination in those with mild-moderate acne. The objective of the present survey was to assess the role of 0.3% adapalene/2.5% BPO combination in those with mild-moderate acne.: A total of 438 healthcare professionals (dermatologists and cosmetologists) participated in the survey, through which their patients’ experiences with the product were recorded. : A significant proportion of the patient population (31%) experienced improvement just after 2 weeks of treatment with the combination. Most patients (84%) also found it easy to include the product in their skincare regime. Most healthcare professionals and patients (>80%) rated the effectiveness and tolerability of the intervention as ‘good’ to ‘excellent’. : The survey confirms the 0.3% adapalene/2.5% BPO combination as an efficacious, easy-to-use topical treatment option for moderate to severe acne with the potential to impact acne scars, in line with findings from other studies examining the effect of this combination.