A case series of bowen’s disease in a tertiary care centre in South India

Abstract

Bowen’s disease is a rare premalignant condition with multifactorial etiology. Usually, Bowen’s disease manifests as solitary, well defined erythematous plaque over sun exposed areas and less commonly over photo protected sites. Hereby we report eight patients with clinical diagnosis of Bowen’s disease confirmed by dermoscopy and histopathology. Dermatological examination revealed presence of pigmented, hyperkeratotic plaques and classical morphology. Scales and glomerular vessels were the most common features in dermoscopy. Histopathology was characteristic with presence of atypical cells in all patients. Five patients were treated with surgical excision, two other patients with 5% imiquimod and 5-fluorouracil creams respectively. One patient was lost to follow up. Post excision biopsy revealed presence of invasive malignancy in two patients. Hence it is important to diagnose and treat Bowen’s disease as early as possible.