The diagnosis of early psoriatic arthritis in patients of psoriasis visiting dermatology outpatient department

Abstract

: Early diagnosis of Psoriatic Arthritis (PsA) in psoriasis patients is crucial but challenging. This study aimed to describe the prevalence, clinical, laboratory, and imaging characteristics of early PsA in a dermatology outpatient setting. : A retrospective study was conducted on 20 psoriasis patients. Clinical, laboratory, and imaging data were collected to identify PsA features. The prevalence of PsA and its correlation with Psoriasis Area and Severity Index (PASI) scores were analyzed.: The prevalence of PsA in the study cohort was 40%. Higher PASI scores were significantly associated with PsA (p=0.001). The most common clinical presentation of PsA was oligoarticular (50%), followed by polyarticular (37.5%) and axial (12.5%) patterns. Laboratory findings showed elevated ESR and CRP levels (p<0.001), but no significant association with rheumatoid markers. Imaging, particularly MRI, was effective in detecting enthesitis (35%). Multivariable analysis identified higher PASI scores and a family history of PsA as significant predictors for PsA development.: The study highlights the high prevalence of PsA among psoriasis patients in dermatology settings. Severe psoriasis, as indicated by higher PASI scores, is a significant predictor of PsA. Early identification and management of PsA are crucial, with MRI being an effective diagnostic tool.