The prospect of probiotics in -induced peptic ulcer disease: A perspective review

Abstract

The relationship between the human host and the intestinal microbiota is dynamic and symbiotic. This review examines whether there is a correlation between a disruption in host-microbial interactions caused by an alternative composition of gut microbiota and an increased susceptibility to peptic ulcer disease, mainly when hazardous bacteria are present in the coexistence. Peptic ulcers frequently arise from infections caused by (), a pathogen that evades the host's immune system and establishes a lifelong colony. This protracted infection gives rise to chronic inflammation, which substantially raises the risk of developing gastric ulcers and gastric cancer. One of the significant obstacles in the treatment of infection is antibiotic resistance, which develops as a result of improper antibiotic treatment for bacterial infections. Such misuse of antibiotics also results in dysbiosis. In such cases, probiotics become an essential tool that restores the balance of the normal flora in the body and eliminates critical infections. This results in probiotics being utilized extensively for ulcer treatment and potentially serving a dual purpose in combating infection; consequently, antibiotic usage will be reduced, and human health will advance.