Frequency of Hepatitis E virus infection in patients with acute hepatitis

Abstract

Hepatitis E virus causes a self-limiting viral infection, transmitted by feco-oral route. HEV infection is major health problem worldwide, with a higher incidence in developing country.To determine the frequency of HEV infection in patient with acute hepatitis and describe the frequency of HEV in different sex and age groups. From January 2019 to December 2020, Serum samples from clinically suspected acute viral hepatitis cases were collected and sent to the department of microbiology maintaining precautions. These were processed for the detection of HEV- specific Immunoglobulin M antibodies carried out rapid card test which is based on immunochromatography.The seroprevalence of HEV (11.79%), HEV infection is slightly higher in female (52%) as compare to male (48%) and HEV infection was most commonly seen in adults (age group 21-30 years)The best means of reducing the spread of infection is by promoting simple measure of personal and community hygiene. However, these data will be useful for planning of future vaccination and for better sanitation. This study also helps the local organizations for maintaining the proper hygiene condition and supply purified water which can help to reduce the prevalence of Hepatitis E virus.