Investigating the function of serum B-HCG levels in the prognosis of hypertensive pregnancy disorders: A prospective observational study

Abstract

Pregnancy-related hypertensive diseases are a serious hazard to world health. Identifying predictive markers is crucial for timely intervention. Serum β-HCG, known for its diverse role in pregnancy, is explored due to its potential involvement in vascular remodeling and angiogenesis. The prospective observational study involves 200 pregnant women, monitored from early gestation to delivery. Serum β-HCG levels are evaluated at different time points. Data collection includes clinical assessments, obstetric evaluations, and blood sample analysis. Statistical analysis is conducted using MedCalc software. Among 200 cases, elevated serum β-HCG levels (≥2 MoM) show a higher prevalence of hypertensive disorders (HDOP) compared to lower levels (<2 MoM). Maternal and fetal outcomes are explored, revealing adverse outcomes associated with elevated β-HCG levels. Age, religion, and parity distributions are analyzed for their correlation with HDOP. The study establishes a strong correlation between the onset of HDOP and increased β-HCG levels. There is no discernible relationship between age and HDOP, while religious variations and parity suggest potential relationships. The study also highlights a significant link between proteinuria and HDOP. For a thorough understanding, more studies with bigger sample numbers and controlled designs are advised.