Transitional meningioma benign who grade 1 tumor-A case and review of the literature

Abstract

Transitional meningioma (TM) is an uncommon benign meningioma. Transitional meningioma is a WHO grade I meningioma characterized by the coexistence of meningothelial cells and fibrous architectural patterns. A35 year female presented with history of intermittent fever, headache of 1 month duration. And since last 2 days with altered level of consciousness and vomiting.: MRI of the brain was performed using TI weighted spin echoI2 weighted turbo spin echo and turbo Fluid-attenuated inversion recovery: FLAIR diffusion sequences. It showed a large, lobulated, enhancing lesion in right fronto-temporal region, along right greater wing of sphenoid suggestive of meningioma. Surgical excision of tumor was done. On histopathology showed a benign tumor consists of meningothelial and fibrous proliferation. The meningothelial cells were arranged in fascicles, with the fibroblastic tumor in syncytial pattern. The nuclei were round, uniform without nucleoli. The chromatin was fine and open. The tumor cells were spindle having abundant pink cytoplasm, indistinguishable cell membranes and bland nuclear features. Mitotic figures and atypia were absent .Scattered Psammoma bodies were noted. Histopathological diagnosis was gives as benign WHO grade 1 tumor- transitional meningioma.Due to enhanced and improved imaging, histopathological techniques the increased incidence of meningiomas is observed and it will be helpful for better outcomes of patients. We are presenting this case of transitional meningioma benign tumor WHO grade1for its clinical, radioimaging and histopatholgical findings.