Affiliation:
1. KS Hegde Medical Academy Deralakatte, Mangalore, Karnataka, India
Abstract
Phyllodes tumors are rare fibroepithelial neoplasms of the breast, classified as benign, borderline, or malignant based on histological features. Osseous metaplasia, characterized by the presence of bone formation within the tumor, is an uncommon finding. This case report highlights the rarity of osseous metaplasia in a benign phyllodes tumor.A 23-year-old female presented with a gradually enlarging lump in the left breast. Mammography and cytological diagnosis were suggestive of giant fibroadenoma. Surgical excision was done and a histopathological diagnosis of benign phyllodes tumor with osseous metaplasia was made.The occurrence of osseous metaplasia in a benign phyllodes tumor is exceptionally rare. Differentiating this phenomenon is essential for accurate diagnosis and appropriate management. Further research is needed to understand the underlying mechanisms and clinical implications of osseous metaplasia in phyllodes tumors.
Publisher
IP Innovative Publication Pvt Ltd
Reference11 articles.
1. Christensen LG, Caterino T Di, Talman ML , Phyllodes tumor with a benign heterologous osseous component: a diagnostic challenge.APMIS 2019;127(6):484-8
2. Choudhary A, Agarwal D, Goyal D, Kalra R, Choudhary A, Heterologous osseous differentiation in Malignant Phyllodes tumour - A rare case report.IAIM 2016;3(8):270-3
3. Alyami H, Al-Osail E, Harbi S, Bshait M Bu, Benign osseous metaplasia of the breast: Case report.Int J Surg Case Rep 2018;44:90-2
4. Krishnamurthy J, Osseous differentiation in cystosarcoma phyllodes - diagnosed by fine needle aspiration cytology.J Cytol 2010;27(4):149-51
5. Zhang Y, Kleer CG, Phyllodes Tumor of the Breast: Histopathologic Features, Differential Diagnosis, and Molecular/Genetic Updates.Arch Pathol Lab Med 2016;140(7):665-71