thrombolytic activity study of a polyherbal formulation developed by using extracts of different medicinal plants

Author:

Kumar Prusty Amiya,Muduli Avinash1,Kumar Rout Susanta2

Affiliation:

1. Institute of Pharmacy & Technology, Salipur, Odisha, India

2. I

Abstract

The present research work was carried out to evaluate the in-Vitro thrombolytic activity of a polyherbal formulation prepared by using extracts of different part of medicinal plants, having thrombolytic activity i.e. bulbs of cepa and seeds of The extracts had shown 38.93 % and 35.65 %, clot lysis activity respectively, that was significant with reference to Streptokinase (64.97 %) and water (1.26%). The formulated poly herbal formulation using these two extracts also had shown good thrombolytic activity. The phytochemical analysis of individul plant extract had shown presence of different phytochemicals in common. That indicates, the in-vitro thrombolytic activity of the plants may be due to the presence of these phytochemicals.

Publisher

IP Innovative Publication Pvt Ltd

Subject

General Earth and Planetary Sciences,General Environmental Science

Reference12 articles.

1. Sherwani S K, Bashir A, Haider S S, Shah M A, Kazmi S U, Thrombolytic Potential of Aqueous and Methanolic Crude Extracts of Camellia sinensis (Green Tea): In vitro study.J Pharmacogn Phytochem 2013;2(1):125-9

2. Fathima S N, Ahmad S V, Kumar B R, Evaluation of In Vitro Thrombolytic Activity of Ethanolic Extract of Curcuma Caesia Rhizomes.Int J Pharma Res Rev 2015;4(11):50-4

3. Sayeed M A, Kabir H, Rashid M, Bhuiyan M, Ahamad F M, Rashid M A, Thrombolytic Activity of Methanolic Extracts of Desmodium paniculatum (L.) and Sarcochlamys pulcherrima (Roxb.Bangladesh Pharm J 2014;17(1):67-9

4. Coronary Thrombolysis: Streptokinase or Recombinant Tissue-Type Plasminogen Activator?

5. Sustained reflow in dogs with coronary thrombosis with K2P, a novel mutant of tissue-plasminogen activator

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