ADR assessment of isoniazid induced psychosis: Case report and review of literature

Author:

Kurup Karan Krishna1ORCID,Shamabanu KP1,Khadeejathul Nifana Nasrin NK1,Hafshath MM1,Karim Muhammed Sinan Abdul1

Affiliation:

1. Baby Memorial Hospital, Kannur, Kerala, India

Abstract

Tuberculosis ranks among the top 10 causes of death globally and stands as the primary cause attributed to a single infectious agent. Among all antitubercular drugs, Isoniazid is most important role in the management of pulmonary tuberculosis.Various neuropsychiatric adverse effects have been documented in association with the use of isoniazid, both in therapeutic and overdose scenarios. This case report describes a 68-year-old male with multiple health issues, including disseminated tuberculosis, developed drug-induced psychosis, likely due to isoniazid in his anti-tubercular therapy. This case underscores the challenges of psychiatric adverse effects in tuberculosis treatment and emphasizes the importance of prompt recognition and intervention.

Publisher

IP Innovative Publication Pvt Ltd

Subject

General Earth and Planetary Sciences,General Environmental Science

Reference18 articles.

1. Chand S, Bhandari R, Girish HN, Sukeerthi D, Isoniazid Induced Psychosis.J Glob Pharma Technol 2019;11(5):11-4

2. Bangwa R, Rawat J, Joshi Y, Isoniazid Induced Psychosis: A Case Report.J Pharm Res Clin Pract 2020;3(1):23-5

3. Kaur T, Kaur K, Malhotra P, Isoniazid Induced Psychosis: A Case Report.J Nepal Paediatric Soc 2019;39(3):189-92

4. , DruBank Isoniazid..

5. Arya S, Sukhija G, Singh H, Acute psychosis after recent isoniazid initiation.Journal of clinical and diagnostic research: JCDR 2015;9(6):45-55

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