A review on potential anti-diabetic herbs and polyherbal formulations concept

Abstract

Multifactorial diseases, for diabetes develop various complication like hepatic toxicity, retinopathy, neuropathy, nephropathy and immunodeficiency etc. Numerous medicinal herbs have been used for the diabetes mellitus in traditional systems of medicine worldwide as they are a great source of phytochemical constituents and many of them are known to be effective against diabetes. Medicinal herbs with antidiabetic activities are being more desired, to lesser side effect and low cost. The efficacy of antihyperglycemic herbs is achieved by increasing insulin secretion, enhancing glucose uptake, activate GLP and inhibiting glucose production. The antidiabetic herbs contains many phytochemical constituents they single herb use produce mild effect when the combining of two — three herbs which having different chemical constituent and pharmacological action and produce synergistic effect and avoid repeated dose and achieve the efficacies therapeutic effec.