Green synthesis of silver nitrate (AgNO) mediated herbal antimicrobial aqueous extracts of Ocimum basilicum (Basil Leaves)

Abstract

Green antimicrobial herbal preparations have emerged as cost effective, non-toxic and sustainable approach that involves the use of eco-friendly and non-toxic plant herbs and spices extracts. Green synthesis of silver-treated herbal extracts of Ocimum basilicum (basil leaves extracts) is well known for its safe and cost-effective approach due to having antimicrobial activity to treat various influenza like symptoms, antistress and antidepressant properties.  Herbal plant leaf extracts have also been reported to contain an active reducing agent that can reduce metal ions to synthesize biogenic metal nanoparticles. Silver itself, is well reported for their bactericidal properties and also enhance antimicrobial properties when used to prepare biogenic silver nanoparticles from herbal and other biological sources. Hence, we prepared silver nitrate (AgNO) mediated herbal formulations of (basil extracts) that showed significant antibacterial activity against gram-negative bacteria, Escherichia coli BL21 strain. Moreover, this green approach can be more promising to prepare antimicrobial of silver-treated formulations using Ocimum basilicum extracts. It might be safe and cost effective herbal based preparations including nanosuspensions that can further proposed for clinical practices to treat various microbial pathogenesis.