A comprehensive review on preliminary screening models for the evaluation of anti-cancer agents

Abstract

Cancer refers to a category of illnesses characterised by uncontrolled growth of new cells. The screening of an anticancer drug is a time-consuming procedure that requires several in-vitro, in-vivo, and clinical investigations. Toxic dosages of screening pharmaceutical drugs in-vivo at varying concentrations need to be envisioned in order to prevent chemical poisoning in animals throughout an experiment. Cancer management has been the subject of several in-vitro and in-vivo investigations. To determine the test compound's anti-cancer efficacy, this research compiled a review of in vivo and in vitro assays. Here, the study emphasizes on the numerous preclinical approaches and processes used in anticancer research.