Evaluation of phytochemicals, antioxidant property and effects ofcultivated at foothill area of Uttarakhand on hyperglycemic rats

Abstract

Cichorium (C.) intybus is an important medicinal herb has been used in Ayurveda, Unani and Siddha System of Medicine for treatment of liver, stomach, kidney and skin diseases. It is also used as blood purifier, antipyretic and antibacterial. Free radicals or highly reactive oxygen species are capable of inducing various degenerative diseases through oxidative damage to cells/organs in human being. The study was aim to determinate the phytochemical characterization and evaluates the antioxidant property and effects of cultivated in foothill area of Uttarakhand on hyperglycemic rats. The antioxidants compounds of the were also determined. Leaves and roots of Kasni plant are rich in phytochemicals and antioxidant compounds, but significant (P<0.05) difference in phytochemicals and antioxidant property were observed between two parts leaves and roots of the plants. The leaf extract of the plant was also exhibited significantly (P<0.05) effects on hyperglycemic rats. Hence, both parts leaf and root of chicory plant can be used in prevention and treatment of hyperglycemia, hyperlipidemia, and maintaining normal blood biochemical parameters as well as in reduction of oxidative stress in human being.