To correlate clinical profile & laboratory parameters with final outcome in Plasmodium vivax (Pv) and Plasmodium falciparum (Pf) malaria

Abstract

A total of 230 confirmed cases of malaria were taken up for the study from the admitted patients in MGM Medical College & M. Y. Hospital, of which 141 were falciparum positive, 69 were vivax positive & 20 patients were positive for both Pf & Pv.Comparison of duration of stay in Plasmodium falciparum and Plasmodium vivax malariaP value < 0.001 highly significant; <0.05 significant; >0.05 not significant, Comparison of hematological parameters in Plasmodium falciparum and Plasmodium vivax malaria P value < 0.001 highly significant; < 0.05 significant; > 0.05 not significant. Cerebral malaria is the most lethal entity of severe malaria and children are more prone than other susceptible groups. Encephalopathy, shock and renal failure at the time of presentation were poor prognostic factors, while anemia and thrombocytopenia were not found to be associated with adverse outcome.Thrombocytopenia is a key indicator of malaria infebrile patients. Nature of thrombocytopenia in malaria is benign, mostly recovering with antimalarials without platelet transfusions. In our study, mortality rate of malaria was found to be 4.7%. Pf was associated with higher mortality rate as compared to Pv. Complications were more common with Pf group, though they were also seen in Pv group.