Evaluation of antimicrobial properties of conventional poly methyl methacrylate denture base resin materials containing silver doped titanium dioxide nanoparticles against cariogenic bacteria and candida albicans

Abstract

The main aim of the study was to find the antimicrobial properties of a poly methyl methacrylate resin (PMMA) which is modified with silver-doped titanium dioxide nanoparticles. This research study was done to prove that the incorporation of silver-doped TiO2 nanoparticles improves the antimicrobial and antifungal properties.The poly methyl methacrylate resin (PMMA) powder was modified using 0 wt%(control) 1wt% and 3wt% silver doped TiO2 nanoparticles Test specimens were prepared of dimensions 5 mm × 5 mm × 2 mm. The antimicrobial properties of the specimens were evaluated by calculating CFU/ml. The obtained values were analyzed by one-way analysis of variance (ANOVA), Kruskal Wallis test, and post-hoc Tukey’s test at a significance level of 5%. The incorporation of silver-doped titanium dioxide nanoparticles into denture base resin improved antimicrobial activity. Compared to 1% and 3% nanoparticle doped, 3% has given better antimicrobial activity calculated using CFU/ml. It is reduced to one-fourth the microbial growth compared to the control group. The addition of silver-doped titanium dioxide nanoparticles to denture base resin is an effective method for antimicrobial and antifungal action.