Affiliation:
1. Subbaiah Institute of Medical Sciences, Shivamogga, Karnataka, India
Abstract
Allergic rhinitis (AR) is one of the most common disease in India. The association between eosinophils and allergic diseases has been known since many years. To correlate Nasal smear eosinophilia (NSE), blood absolute eosinophil count (AEC) and total serum IgE levels with severity of the clinical score in patients with allergic rhinitis. This is one-year prospective study in patients (n=60) presented with allergic rhinitis to our institute. After taking consent, all the study participants were subjected for blood AEC, IgE levels and nasal smears for eosinophils. Among the samples, 81.7% were males. The mean age of patients was 35.2 years. AEC > 440 cells/cu.mm was seen in 46.6%, NSE>10% in 81.6% and total serum IgE was elevated > 100 IU/ml in 95.0%. There was a good correlation of NSE and serum IgE with the severity of disease. There was no correlation of blood AEC with the severity of clinical score. Data was analysed using SPSS software.rn NSE and IgE both correlated well with severity of the disease. Nasal smear cytology is a simple procedure having good correlation with severity of clinical score should be used routinely. Testing for serum IgE levels will increase the accuracy with a better diagnostic utility.
Publisher
IP Innovative Publication Pvt Ltd
Reference16 articles.
1. Kumar V, Abbas A K, Aster J C, Robbins and Cotran Pathologic Basis of Disease; Diseases of the immune system.9th Edn..201
2. Jagadeeshwar K, Venumadhav V, Sangram V, Chowdary S, Rani S, Kumar V, A study on serum Ige levels, peripheral eosinophils and individual symptoms in patients with non-infective rhinitis and asthma and related conditions research article.Int J Pharm Pharm Sci 2012;4(1):88-92
3. Chandrika D, Allergic rhinitis in India: an overview.Int J Otorhinolaryngol Head Neck Surg 2017;3(1):1-6
4. Allergic Rhinitis and Its Impact on Asthma
5. Wang D Y, Niti M, Smith J D, Yeoh K H, Ng T P, Rhinitis:Do diagnostic criteria affect the prevalence and treatment?.Allergy 2002;57(2):150-4