Affiliation:
1. Acharya Shri Chander College of Medical Sciences and Hospital, Jammu, Jammu and Kashmir, India
2. Shri Mata Vaishno Devi Narayana Superspeciality Hospital, Katra, Jammu and Kashmir, India
3. Government Medical College, Srinagar, Jammu and Kashmir, India
Abstract
Colorectal cancer (CRC), which comprises colon and/or rectum cancer, is a significant health problem and the world’s second most fatal cancer. Colorectal adenocarcinoma (CRA), can be divided into 4 grades according to Broder's criteria, i.e., well differentiated (I), moderately differentiated (II), poorly differentiated (III), and undifferentiated (IV). Currently, the TNM classification is considered the gold standard for the establishment of prognosis as well as deciding the type of treatment. The aim of our study was to assess the incidence, gender preponderance, site, histological grading and staging of colorectal carcinoma in our hospital. This is a retrospective study of 75 patients who were diagnosed as colorectal carcinoma from July 2022 to January 2024. The specimen of the cases were sent to our Department of Pathology, Acharya Shri Chandra college of medical sciences and hospital, Jammu for histopathological examination after resection. In our study we found out that the cases of colorectal carcinoma had a male preponderance with most cases ranging from age group 46 to 60. The most common site of occurrence was rectum and the most common histological grade diagnosed as per microscopy was grade ІІ, that is moderately differentiated adenocarcinoma. The highest number of cases were at Stage II, followed by Stage III. There is an urgent need to look upon the alarming rate of colorectal carcinoma and understand its incidence, grading and staging for a better prognosis.
Publisher
IP Innovative Publication Pvt Ltd
Reference19 articles.
1. WHO Cancer..
2. . SR Hamilton, LA Aaltonen, .Carcinoma of the colon and rectum. In: Pathology and genetics of tumours of the digestive system.104-19
3. Hamilton W, Sharp D, Diagnosis of colorectal cancer in primary care: the evidence base for guidelines.Fam Pract 2004;21(1):99-106
4. Cancer Genome Atlas Network Comprehensive molecular characterization of human colon and rectal cancer.Nature 2012;487(7407):330
5. Arnold M, Sierra MS, Laversanne M, Soerjomataram I, Jemal A, Bray F, Global patterns and trends in colorectal cancer incidence and mortality.Gut 2017;66(4):683-91