Comparison of tear function among newly diagnosed polycystic ovary syndrome (PCOS) and PCOS under treatment

Abstract

To compare the tear function among newly diagnosed Polycystic Ovary Syndrome subjects and Polycystic Ovary syndrome under treatment. Seventy Polycystic Ovary Syndrome (PCOS) subjects were included in the study with age ranging from 18 to 35 years, consisting of 35 subjects in group 1 as newly diagnosed PCOS and 35 in group 2 as PCOS under treatment. The subjects underwent comprehensive eye examination and slit lamp examination. Participants were asked to answer the ocular surface disease index (OSDI) questionnaire to know the symptoms of dry eye and the following tests such as Schirmer’s 1 and 2, Tear film break-up test (TBUT) was performed to know the tear functions. No difference was found in OSDI scores when comparing two groups. Both Schirmer’s test and TBUT test were significant. When both the groups are compared Schirmer’s 1 p value for right eye is 0.001, left eye is 0.023.Schirmer’s 2 p value for right eye is 0.002, left eye is 0.001.However TBUT p value for right eye and left eye is 0.00. Through our findings we suggest that patients who are under treatment for PCOS, should take ophthalmic examination, especially for dry eye.