Comparative study of etomidate and fentanyl citrate with propofol (1%) and fentanyl citrate for total intravenous anaesthesia in short surgical procedures

Abstract

Total intravenous anaesthesia (TIVA) is a combination of Induction agents, analgesic drugs and muscle relaxants, excluding simultaneous administration of any inhaled drugs. This study has major objective, to determine the efficacy of Etomidate and Propofol (1%) as anaesthetic induction agents in terms of Induction time, maintenance doses requirements and Recovery parameters. This study suggests that both Etomidate–Fentanyl citrate and propofol (1%)–Fentanyl citrate produced smooth induction, easy maintenance and quick recovery with only minor hemodynamic fluctuations makes them excellent combinations as TIVA technique. Etomidate is preferred over Propofol (1%) especially for hemodynamically unstable patients because of minimal effects on cardiovascular and respiratory system. hypotension and pain on injection was observed more frequently with Propofol (1%) while myoclonus with Etomidate. With these observations in mind and careful selection of patients, both agents appear similarly safe for use in elective and short surgical procedures.